M.Sc. in Biotechnology

2018 - 2020

Indian Institute of Technology Bombay, Mumbai

Project: Computational analysis of d1 receptor modulation by mu-opioid receptor activation in medium spiny neuron (MSN)

Guide: Prof. Rohit Manchanda, IIT Bombay

• Accomplished extensive literature review to elucidate the role of endogenous opioids in the reward system.
• Devised a computational model of the mu-opioid receptors and enkephalin mechanism in the regulation of tonic level and phasic dopamine concentration in MSN.
• Developed a compartmental model to simulate the biophysical properties of the dendritic spine using Python-NEURON simulation.
• Modulated D1 receptors and their effect on intrinsic ion channels present on dendritic spines of MSN.
• Incorporated the dendritic spine model into a complete model of Striatal Neurons using NMODL.

B.Sc. in Microbiology

2015 - 2018

Ramakrishna Mission Vidyamandira, Belur Math

• Grade: First Class
• Major Topics Learned: Microbiology, Ecology, Environmental Biology, Biotechnology, Immunology, Molecular biology, Biochemistry, Biostatistics, Bioinformatics

Associate: Content Production and Delivery

Jul’20 - Jun’22

BYJU’s, Banglore

• Analyzed daily work allocation data using advanced Google Sheets and Excel.
• Used SQL for data extraction and manipulation, and utilized Tableau for data visualization.
• Analyzed teaching material to identify areas for improvement and developed recommendations for changes, resulting in an increase in student engagement by 15%.
• Trained team members to use Google Sheets and advanced PowerPoint techniques.
• Worked on content review, visual content communication, and content design for a short period of time.

Jun’19-Jul’19

Project: A study of diagnostic algorithms of Mycobacterium tuberculosis and non-tuberculous mycobacterial disease

Guide: Prof. Surendra K. Sharma, ex HOD, dept of internal medicine, AIIMS, New Delhi

• Cultured 100+ patient samples to diagnose the presence of Tuberculosis.
• Performed and analyzed the data of microbial staining, GeneXpert System (CBNAAT) and Line probe assay (LPA) to detect M. tuberculosis and multi-drug resistant bacteria.
• Analyzed Mycobacterial growth (MGIT) and Drug Sensitivity Test (DST) data for low bacterial load samples.
• Performed different biochemical tests for the identification of Mycobacteria and Nontuberculous Mycobacteria.

Jun’17-Jul’17

Project: Regulation of histone levels under DNA damaging conditions in the Pathogenic Yeast Candida glabrata

Guide: Dr. Rupinder Kaur, Centre for DNA Fingerprinting and Diagnostics (CDFD) Hyderabad

• Performed sequence analysis of the DNA damage sensor protein kinase RAD53 protein and its gene.
• Designed cloning and knockout primers for CgRAD53 to delineate its link with Histone H4 level depletion.
• Attempted to generate CgRAD53 Knockout strain by homologous recombinationmediated gene deletion strategy.
• Attempted to generate CgRAD53 Knockout via homologous recombination mediated gene deletion strategy.

Jul’19-Dec’19

Project: Cloning, expression and purification of green fluorescence protein (GFP)

Guide: Prof. Kiran Kondabagil, IIT Bombay

• Cloned GFP-6xHis gene into E. coli DH5α cells using pET-28a (+) as a vector.
• Studied the expression of recombinant DNA in E. coli BL 21 after gene transformation using CaCl₂.
• Purified the GFP protein by using Ni-NTA affinity column chromatography.

Jul’19-Dec’19

Project: Drug designing for targeted lung cancer therapy using bioinformatics tools

Guide: Prof. Prasenjit Bhaumik, IIT Bombay

• Sequence alignment of the lung cancer cell surface specific protein Sez6l2 with its homologous superfamily using Clustal X.
• Generation and evaluation of homology model using I-TASSER and WinCoot.
• Docking studies of protein with its inhibitor molecule using AutoDock and PyMOL.

Jan’19-May’19

Project: Isolation and biochemical characterization of microorganisms in tap water

Guide: Prof. Prashant S. Phale, IIT Bombay

• Isolated and cultured a single bacterial strain from tap water and performed gram staining, capsule staining and spore staining to understand bacterial morphology.
• Performed the following biochemical tests for bacterial strain identification: IMViC test, Lactose  Fermentation test, Triple Sugar Iron (TSI) test, Sugar utilization test, Nitrate reduction test, Catalase test, Oxidase test, Urease test, Starch hydrolysis test, Casein hydrolysis test and Hemolysis test.
• Additionally, antibiotic susceptibility test, growth curve determination, Spore Count Assay and T4 Phage enumeration assay were performed.

Jan’19-May’19

Project: A Comparative study between Bovine serum albumin (BSA) and Human serum albumin (HSA)

Guide: Prof. Dulal Panda and Prof. Samir Maji, IIT Bombay

• Computationally analyzed Sequence, Hydrophobicity, Secondary structure, and 3D structure of proteins.
• Analyzed quenching by Acrylamide, Trp fluorescence, and ANS binding using a spectrofluorometer.
• Studied protein denaturation using heat and GnHCL in far & near UV Circular Dichroism and fluorescence.

2020

• Secured All India Rank 142 out of 10313 candidates in the GATE Biotechnology exam.

2019

• Selected among India’s top 300 candidates by the Indian Academy of Sciences for the IASc-INSA-NASI summer research fellowship for life science.

2018

• Secured All India Rank 60 out of 80,000 candidates in the junior research fellowship programme of the CSIR NET Life Science exam.
• Secured All India Rank 42 out of 4559 students in IIT JAM Biotechnology entrance exam.
• Secured All India Rank 26 out of 7950 students in the IIT JAM Biological Science entrance exam.

2017

• Selected among India’s top 250 candidates by the Indian Academy of Sciences for the IASc-INSA-NASI summer research fellowship for life science.

2020

• Poster presentation on “Decoding behavioral feature selection by Striatal neurons - Computational Approach” at the genevision event, IIT Bombay.

2019

• Oral presentation on “Application of Fluorescence in early detection, diagnosis and quantification of dental caries” at a departmental colloquium organised by BSBE, IITB.

2017

• Oral presentation on “Regulation of histone levels under DNA damaging conditions in the Pathogenic Yeast Candida glabrata” at the Fourth Annual TCIS Summer Research Symposium organised by Tata Institute of Fundamental Research (TIFR), Hyderabad.
• Oral presentation on Candida glabrata research at a symposium organised by the Center for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad.

2020

• Attended a seminar on “Empowering Normal Cells Against Cancer” by Prof. Vivek M. Rangnekar, Cancer Cell Biology Research Program, University of Kentucky.
• Attended a seminar on “The ecology and evolution of host-microbial associations” by Prof. Deepa Aghashe, National Centre for Biological Sciences.

2019

• Attended a seminar on “Linking Infectious Disease Research to Community Ecology: Understanding multispecies, multiscale host-parasite interactions” by Dr. Debapriyo Chakraborty, Senior Research Scientist, EcoHealth Alliance, New York.

Department Placement Coordinator

Placement Team, IIT Bombay

Jul’19-Jul’20

• Assisted managers and recruiters with on-campus placements for over 300 students.
• Executed placement resume verification process of 1600+ students within a team of 55 DPCs across 21 departments.
• Organized 52+ intra and inter-department level placement preparatory activities such as mock personal interviews, online and offline tests, and group discussions as a single point of contact.

Creative Manager

Symbiotek, Department of Biological sciences and Bioengineering, IIT Bombay

Jul’19-Jul’20

• Led a team of 6 people to create posters and a website for BSBE annual departmental event Genvison.
• Mapped out event planning, research showcase and ideated new marketing campaigns which increased footfall by 10%.

Institute Exchange Programme Buddy

International Relation office, IIT Bombay

Jan’19-May’19

• Accompanied and ensured a smooth integration of the 42 inbound International exchange students.
• Worked as part of a 20-member team to maintain good international relations with foreign universities.

Sports

2019

• Actively participated in inter-department Kho Kho match at IIT Bombay.

2018

• Achieved 3rd position with my team in intra hostel general Table Tennis championship.

Cultural

2019

• Stood 3rd in a group dance competition organized by PG Cult Phase II, IIT Bombay.

2018

• Secured 3rd position in “short advertise movie-making competition” organized by PG Cult Phase I, IIT Bombay.

Social

2019

• Volunteered in 136th Versova Beach cleanup campaign organized by Abhyday IIT Bombay.

2015-2016

• Actively involved as an ‘NSS volunteer’ for 1 year and with a team of 200+ students organized 10+ social activities like Blood donation camps, Eye checkup camps, etc

Others

2018

• Lead Trainer in the Student Solar Ambassador Program organized by TechFest IIT Bombay which made a Guinness world record entitled “The Most LED lights lit simultaneously”

• Led 9 organizers to execute 12 events in Asia’s largest college cultural festival Mood Indigo, IITB.